Article

Newly identified relatives of botulinum neurotoxins shed light on their molecular evolution

2017-11-17

Abstract excerpt

The evolution of bacterial toxins is a central question to understanding the origins of human pathogens and infectious disease. Through genomic data mining, we traced the evolution of the deadliest known toxin family, clostridial neurotoxins, comprised of tetanus and botulinum neurotoxins (BoNT). We identified numerous uncharacterized lineages of BoNT-related genes in environmental species outside of Clostridium...

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Literature Corpus work: 793c05fe-466d-53ed-a063-48d8aa375a5c
DOI: 10.1101/220806

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