Article

Comprehensive lipidomics reveals reduced hepatic lipid turnover in NAFLD during alcohol intoxication

2021-02-19

Abstract excerpt

<h4>Background & Aims</h4> In experimental models, alcohol induces acute changes in lipid metabolism that cause hepatocyte lipoapoptosis and inflammation. Here we study human hepatic lipid turnover during controlled alcohol intoxication. <h4>Methods</h4> We studied 39 participants with three distinct hepatic phenotypes: alcohol-related liver disease (ALD), non-alcoholic fatty liver disease (NAFLD), and healthy con...

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Literature Corpus work: 788100a6-5c70-5abe-9f01-c9f0f16fcdec
DOI: 10.1101/2021.02.18.21251910

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