Article
Site-specific analysis of the SARS-CoV-2 glycan shield
2020-03-28
Abstract excerpt
The emergence of the betacoronavirus, SARS-CoV-2 that causes COVID-19, represents a significant threat to global human health. Vaccine development is focused on the principal target of the humoral immune response, the spike (S) glycoprotein, that mediates cell entry and membrane fusion. SARS-CoV-2 S gene encodes 22 N-linked glycan sequons per protomer, which likely play a role in immune evasion and occluding immun...
Topics
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- Animal Virus Infections Studies
- Bacteriophages and microbial interactions
- Immunotherapy and Immune Responses
- Influenza Virus Research Studies
- Monoclonal and Polyclonal Antibodies Research
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Viral gastroenteritis research and epidemiology
Identifiers and source
- Literature Corpus work
- 778f38e7-3190-50b3-a63f-8f970b3012af
- DOI
- 10.1101/2020.03.26.010322
