Article

Viral replication probably promoted by EV71 VP4 protein via activating the PI3K/AKT and MAPK pathways in RD cell

2022-11-10

Abstract excerpt

Enterovirus 71 (EV71) internal capsid protein (VP4) conserves in picornaviridae family and plays critical role in viral infection and replication by unknown mechanisms. In this study, mRNA sequencing was performed to analyze Differentially Expressional Genes (DEGs) in VP4 protein overexpressing Human Rhabdomyosarcoma Cells. It had been showed that Focal Adhesion, PI3K/AKT and MAPK pathways were mainly activated by...

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Literature Corpus work: 775486b6-5c7a-5e12-a3a9-386acf0c89ce
DOI: 10.21203/rs.3.rs-2233537/v1

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