Article

Cortico-autonomic local arousals and heightened somatosensory arousability during NREM sleep of mice in neuropathic pain

2021-01-07

Abstract excerpt

Chronic pain patients frequently suffer from sleep disturbances. Improvement of sleep quality alleviates pain, but neurophysiological mechanisms underlying sleep disturbances require clarification to advance therapeutic strategies. Chronic pain causes high-frequency electrical activity in pain-processing cortical areas that could disrupt the normal process of low-frequency sleep rhythm generation. We found that th...

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Literature Corpus work: 774694f2-b273-579e-b2ac-2d32ff640f9a
DOI: 10.1101/2021.01.04.425347

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