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Zebrafish <i>carbohydrate sulfotransferase 6</i> ( <i>chst6</i> ) mutants provide a preclinical model for macular corneal dystrophy

2024-01-25

Abstract excerpt

Macular corneal dystrophy (MCD) is a rare congenital disease caused by mutations in the carbohydrate sulfotransferase 6 ( chst6 ) gene. Patients suffer from opaque aggregates in the cornea leading to bilateral progressive vision loss by 4 th decade of life. Corneal transplantation is the only available treatment, which is invasive, not available to every patient and recurrence of the symptoms is common. Keratoc...

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Literature Corpus work
7708b715-5d6c-510c-9129-644740f18c0c
DOI
10.1101/2024.01.24.577150
Open publication

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