Article

The ratio of interacting miRNAs’ expressions is a robust biomarker for disease classification in multi-center data

2023-07-06

Abstract excerpt

<h4>Background</h4> Many miRNA-based diagnostic models have been constructed to distinguish diseased individuals. However, due to the inherent differences across different platforms or within multi-center data, the models usually fail in the generalization for medical application. <h4>Results</h4> Here, we proposed to use the within-sample expression ratios of related miRNA pairs as markers, by utilizing the inter...

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Literature Corpus work: 76b8cafe-019f-5526-a2bf-670c076415af
DOI: 10.1101/2023.06.29.23291976

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