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In Vitro Efficacy of Cyclosporine A and Various Antiseptics and Antiviral Drugs on Adenovirus Genotype 8, a Common Cause of Epidemic Keratoconjunctivitis

2022-01-05

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<title>Abstract</title> <p><bold>Purpose: </bold>To evaluate the in vitro efficacy of cidofovir, ganciclovir, povidone iodine, chlorhexidine, and cyclosporine A on adenovirus genotype 8<bold> Methods:</bold> Conjunctival samples were collected from patients with adenoviral conjunctivitis and cultured in A549 cells. Adenovirus diagnosis was confirmed by RT-PCR. For each drug, the 50% cytotoxic concentration (CC₅₀)...

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Literature Corpus work
76a673a2-5036-513c-9bf7-66ed41e721bf
DOI
10.21203/rs.3.rs-1189810/v1
Open publication

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