Article

Tenascin-c Knockdown Suppresses Vasculogenic Mimicry of Gastric Cancer by Inhibiting ERK- Triggered EMT

2021-02-11

Abstract excerpt

<h4>Background: </h4> Gastric cancer is one of the most common malignancies worldwide and vasculogenic mimicry (VM) is considered to be the leading cause for the failure of anti-angiogenesis therapy in advanced gastric cancer patients. Tenascin-c (TNC) plays a pivotal role in VM. Thus, we explored the role of TNC in VM formation in gastric cancer. <h4>Methods: </h4> Gastric cancer tissues and corresponding adjacen...

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Literature Corpus work: 76716085-d909-5edc-bee3-262a473f02ad
DOI: 10.21203/rs.3.rs-205699/v1

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