Article

Transcriptional responses to <i>in vitro</i> macrocyclic lactone exposure in <i>Toxocara canis</i> larvae using RNA-seq

2024-12-20

Abstract excerpt

Toxocara canis , the causative agent of zoonotic toxocariasis in humans, is a parasitic roundworm of canids with a complex lifecycle. While macrocyclic lactones (MLs) are successful at treating adult T. canis infections when used at FDA-approved doses in dogs, they fail to kill somatic third-stage larvae. In this study, we profiled the transcriptome of third-stage larvae derived from larvated eggs and treated in...

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Literature Corpus work: 75bba183-a0f7-59b2-a550-a0270c0d4765
DOI: 10.1101/2024.12.20.629602

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Transcriptional responses to <i>in vitro</i> macrocyclic lactone exposure in <i>Toxocara canis</i> larvae using RNA-seqDOI 10.1101/2024.12.20.629602Read

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