Genetic differences in host infectivity affect disease spread and survival in epidemics

Abstract excerpt

Survival during an epidemic is partly determined by host genetics. While quantitative genetic studies typically consider survival as an indicator for disease resistance, mortality rates of populations undergoing an epidemic are also affected by tolerance and infectivity (i.e. the propensity of an infected individual to transmit disease). Few studies have demonstrated genetic variation in disease tolerance, and no...

Topics

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• Bayes Theorem
• Computer Simulation
• Disease Outbreaks
• Disease Transmission, Infectious
• Genetic Predisposition to Disease
• Models, Genetic
• Models, Statistical
• Multifactorial Inheritance

Identifiers and source

Literature Corpus work

7551496e-17e9-562f-bbf8-88e6c3ea9eb9

DOI

10.1101/483602