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Article

Indirect genetic effects and the spread of infectious disease: are we capturing the full heritable variation underlying disease prevalence?

PloS one - 1 Jan 2012

Lipschutz-Powell Debby, Woolliams John A, Bijma Piter, Doeschl-Wilson Andrea B

Abstract excerpt

Reducing disease prevalence through selection for host resistance offers a desirable alternative to chemical treatment. Selection for host resistance has proven difficult, however, due to low heritability estimates. These low estimates may be caused by a failure to capture all the relevant genetic variance in disease resistance, as genetic analysis currently is not taylored to estimate genetic variation in...

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PMID: 22768088
DOI: 10.1371/journal.pone.0039551
PMCID: PMC3387195

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