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Association Tests Using <b>Co</b> py <b>N</b> umber Profile <b>Cur</b> ves (CONCUR) Enhances Power in Rare Copy Number Variant Analysis

2019-06-10

Abstract excerpt

Copy number variants (CNVs) are the gain or loss of DNA segments in the genome that can vary in dosage and length. CNVs comprise a large proportion of variation in human genomes and impact health conditions. To detect rare CNV association, kernel-based methods have been shown to be a powerful tool because their flexibility in modeling the aggregate CNV effects, their ability to capture effects from different CNV f...

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Literature Corpus work: 74b9d63c-3100-5004-a987-794f7bbff4f1
DOI: 10.1101/666875

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