Article

Discovering compounds mimicking calorie restriction using mammalian gene expression profiles

2020-06-03

Abstract excerpt

Obesity is a risk factor for cardiovascular diseases, diabetes and cancer. In theory the obesity problem could be solve by the adherence to a calorie restricted diet, but that is not generally achieved in practice. An alternative is a pharmacological approach, using compounds that trigger the same metabolic changes associated with calorie restriction. Here I expand in the pharmacological direction by identifying c...

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Literature Corpus work: 747dcb4e-d52e-59a7-b402-bbe105404fe2
DOI: 10.1101/2020.06.03.131219

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