The direct/inverse interplay among 5-hydroxymethylcytosine (5hmC)-related biological pathways in gastrointestinal pan-cancer study

Abstract excerpt

5-hydroxymethylcytosine (5-hmC) as an epigenetics marker has significant impacts on cancer progression. Identification of preserved 5-hmC-related subnetworks in pan-cancer studies could lead to a better understanding of gastrointestinal (GI) cancers insights. Here, we conducted a network-based analysis on 5-hmC values of GI cancers, including colon, gastric, pancreatic cancers, and healthy donors. The co-5-hmC net...

Topics

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• Gastric Cancer Management and Outcomes
• Gastrointestinal Tumor Research and Treatment
• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Gene Regulatory Networks
• Helicobacter pylori-related gastroenterology studies
• Mutation
• Neoplasms

Identifiers and source

Literature Corpus work

73f4fd83-bcb9-521a-944d-f7f25fc03423

DOI

10.21203/rs.3.rs-842553/v1