Article

The Construction of Polygenic Risk Scores for Breast Cancer Based on LightGBM and Multiple Omics Data

2021-04-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Breast cancer accounts for a large proportion of cancer-related deaths in women. Polygenic risk score (PRS) derived from single nucleotide polymorphisms (SNP) data can evaluate the individual-level genetic risk of breast cancer and has been widely applied for risk stratification. However, standalone SNP data used for PRS may not provide satisfactory prediction a...

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Literature Corpus work: 73a8a57c-f187-5fba-a5c5-61d8296719c4
DOI: 10.21203/rs.3.rs-438740/v1

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