Article

The adipocyte plasma membrane proteome and its role in drug-induced metabolic toxicity

2019-01-01

Abstract excerpt

Although antiretroviral therapy (ART) has increased the life expectancy of HIV patients, chronic administration of antiretroviral drugs has also led to the development of metabolic and cardiovascular complications in these patients. Metabolic syndrome is a major public health burden worldwide and is a risk factor for cardiovascular disease (CVD). The risk of CVD in HIV-patients has doubled in comparison to the gen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 73265dab-c4f4-5bba-bd36-baf5320682eb
DOI: 10.17638/03061364

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The adipocyte plasma membrane proteome and its role in drug-induced metabolic toxicityDOI 10.17638/03061364Read

HIV associated lipodystrophy : study of molecular mechanisms and genetic susceptibilitySemantic proximity Read

A Critical Review of the Biochemical Mechanisms and Epigenetic Modifications in HIV- and Antiretroviral-Induced Metabolic SyndromeSemantic proximity Read

Effect of genetic variations in drug transporters, metabolizing enzyme and regulatory genes on the development of HIV-associated lipodystrophy.Semantic proximity Read

Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapiesSemantic proximity Read

Viral mechanisms of adipose dysfunction: lessons from HIV-1 VprSemantic proximity Read

A Distinct Form of Subcutaneous Fat Fibrosis Predicts Insulin Resistance in People with HIVSemantic proximity Read

Pharmacogenetics of the lipodystrophy syndrome associated with HIV infection and combination antiretroviral therapy.Semantic proximity Read

The role of nucleoside reverse transcriptase inhibitors in the fat redistribution syndrome.Semantic proximity Read

White Adipose Tissue Compositional and Transcriptional Patterns with Progressive Glucose Intolerance in Persons with HIVSemantic proximity Read

Insulin resistance in the HIV-infected population: the potential role of mitochondrial dysfunction.Semantic proximity Read

Follow-up of phenotype and metabolic changes in adult males living with HIV on combination antiretroviral therapy (CART) for a decadeSemantic proximity Read

Pharmacogenetics of the metabolic disturbances and atherosclerosis associated with antiretroviral therapy in HIV-infected patients.Semantic proximity Read