Article

Advances in Newborn Screening for Sickle Cell Disease: A Systematic Review of Diagnostic Methods and Innovations

2025-05-09

Abstract excerpt

Sickle cell disease (SCD) is one of the most prevalent hemoglobinopathies worldwide, particularly in regions with high genetic predisposition. Early diagnosis through newborn screening (NBS) is critical for initiating interventions that significantly reduce morbidity and mortality. This systematic review evaluates the current methodologies used in NBS for SCD, comparing their sensitivity, specificity, and feasibil...

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Literature Corpus work: 7302d664-ff1a-5d4f-a8f5-6bc41b00ddb1
DOI: 10.1101/2025.05.08.25327242

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