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Article

Utility of First-Line Diagnostic Tests and Molecular Methods for Accurate Characterization of Sickle Cell Disorders.

International journal of laboratory hematology - 1 Jun 2026

Yadav Diksha Dev, Chhabra Sanjeev, Hira Jasbir Kaur, Khadwal Alka Rani, Malhotra Pankaj, Bansal Deepak, Trehan Amita, Sharma Prashant, Das Reena

Abstract excerpt

INTRODUCTION: Sickle cell disorders (SCD) are among the commonest symptomatic hemoglobinopathies worldwide. Their diagnosis involves multiple tests, including complete blood count, cation-exchange high-pressure liquid chromatography (CE-HPLC), hemoglobin electrophoresis, sickling tests, and molecular assays. We evaluated the diagnostic utilities of various testing methods for precise classification of SCDs in a...

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Share to Anemia, Sickle Cell
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hemoglobin, Sickle

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Source

Identifiers

PMID: 41765369
DOI: 10.1111/ijlh.70079

Genes

HBB
SCD
SCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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