Article

MiR-188-5p and MiR-141-3p Promote Bladder Cancer Synergistically via Targeting PTEN to Activate AKT/c-MYC Signal Pathway

2021-09-27

Abstract excerpt

MicroRNAs play a key role in the progress of bladder cancer (BC), which may lead to poor prognosis. A single MicroRNA can be used as an independent factor to regulate the progress of BC, while two MicroRNAs can have a synergistic regulatory effect on BC progress. It has been confirmed in our previous studies that miR-188-5p and miR-141-3p demonstrated high expressions in BC tissues and cells, which can promote the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 72eac913-5155-5d8b-bac7-71f5e4087355
DOI: 10.21203/rs.3.rs-846000/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MiR-188-5p and MiR-141-3p Promote Bladder Cancer Synergistically via Targeting PTEN to Activate AKT/c-MYC Signal PathwayDOI 10.21203/rs.3.rs-846000/v1Read

Genome-Wide Screen of miRNAs and Targeting mRNAs Reveals the Negatively Regulatory Effect of miR-130b-3p on PTEN by PI3K and Integrin β1 Signaling Pathways in Bladder CarcinomaSemantic proximity Read

Expression profile of microRNAs in bladder cancer and their application as biomarkersSemantic proximity Read

The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTENSemantic proximity Read

Panel containing four serum microRNAs has potential to diagnose bladder cancerSemantic proximity Read

LncRNA PCAT6 aggravates the progression of bladder cancer cells by targeting miR-513a-5p.Semantic proximity Read

BMSC-derived exosomal lncRNA PTENP1 suppresses the malignant phenotypes of bladder cancer by upregulating SCARA5 expression.Semantic proximity Read

MiR-145-5p Inhibits the Invasion of Prostate Cancer and Induces Apoptosis by Inhibiting WIP1Semantic proximity Read

Exosome-transmitted microRNA-133b inhibited bladder cancer proliferation by upregulating dual-specificity protein phosphatase 1.Semantic proximity Read

MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCaSemantic proximity Read

Silenced lncRNA SNHG14 restrains the biological behaviors of bladder cancer cells via regulating microRNA-211-3p/ESM1 axisSemantic proximity Read

Clinical value and potential pathways of miR-183-5p in bladder cancer: A study based on miRNA-seq data and bioinformatics analysisSemantic proximity Read

Comprehensive Biological Information Analysis of PTEN Gene in Pan-CancerSemantic proximity Read