Article
BMSC-derived exosomal lncRNA PTENP1 suppresses the malignant phenotypes of bladder cancer by upregulating SCARA5 expression.
Cancer biology & therapy - 31 Dec 2022
Liu Shu-Cheng, Cao You-Han, Chen Li-Bo, Kang Ran, Huang Zhong-Xin, Lu Xin-Sheng
Abstract excerpt
LncRNAs can be transported to tumor cells where they exert regulatory effects by bone marrow mesenchymal stem cells (BMSC)-derived exosomes. Here, we aimed to investigate the functional mechanism of BMSC-derived exosomal lncRNA PTENP1 in the progression of bladder cancer (BC). Methods of BMSC were identified by detecting surface markers through flow cytometry. Exosomes from BMSC were identified by transmission...
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