Article

Diagnostic utility of telomere length measurement in a hospital setting

2017-12-06

Abstract excerpt

Very short telomere length (TL) provokes cellular senescence in vitro , but the clinical utility of TL measurement in a hospital-based setting has not been determined. We tested the diagnostic and prognostic value of TL measurement by flow cytometry and fluorescence in situ hybridization (flowFISH) in individuals with mutations in telomerase and telomere maintenance genes, and examined prospectively whether TL al...

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Literature Corpus work: 72d2afce-d424-52d0-8ebb-3faa281de887
DOI: 10.1101/225797

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