Article

Merging Adaptive Designs with Dynamic Infectious Disease Models Allows Faster and more Accurate Diagnostic Test Accuracy Studies in the Case of an Epidemic

2025-11-27

Abstract excerpt

<h4>Background</h4> During epidemics with emerging infections, diagnostic tests directly inform model-based decision-making and thereby shape infection control strategies. However, diagnostic accuracy studies (DTA) assessing the validity of these tests must be conducted under severe time and data constraints. We investigated whether the integration of adaptive designs and of epidemic spread modelling for prevalen...

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Literature Corpus work: 71c64d3a-0584-547c-8a73-e552cb499b9d
DOI: 10.1101/2025.11.25.25340962

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