Article

GPX4-associated Sedaghatian Type Spondylometaphyseal Dysplasia: A Protein Interactome Perspective

2022-02-19

Abstract excerpt

S pondylo m etaphyseal d ysplasia, S edaghatian type (SMDS) is a rare and lethal skeletal dysplasia inherited in an autosomal recessive manner and caused by mutations in GPX4. In order to expand the functional landscape of this poorly studied disorder and accelerate the discovery of biologically insightful and clinically actionable targets, we constructed SMDS-centric and GPX4-centric protein-protein interactio...

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Literature Corpus work: 715194fd-822e-554c-8426-1c603a796edd
DOI: 10.1101/2022.02.17.479371

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GPX4-associated Sedaghatian Type Spondylometaphyseal Dysplasia: A Protein Interactome PerspectiveDOI 10.1101/2022.02.17.479371Read

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