Genomic risk profiling in advanced maternal age: a Tamil Nadu prenatal study

Abstract excerpt

Background Advanced maternal age (AMA; > = 35 years) is associated with increased fetal chromosomal risk and is an important indication for invasive prenatal diagnosis. This study evaluates karyotyping and chromosomal microarray analysis (CMA) findings among AMA pregnancies in Tamil Nadu, India. Methods In this prospective observational study, 2,200 pregnant women aged ≥35 years who underwent amniocentesis between...

Topics

Open a Topic to create a Post that cites this publication.

• Folate and B Vitamins Research
• Genomic variations and chromosomal abnormalities
• Prenatal Screening and Diagnostics

Identifiers and source

Literature Corpus work

71500909-7f4c-50b9-9c0c-3b59513ff0ef

DOI

10.3389/fmed.2026.1864106