Article

<i>Lactobacillus casei</i>Shirota intervention modulates the esophageal microbiome composition in Barrett’s esophagus

2025-05-13

Abstract excerpt

<h4>Objective</h4> Esophageal adenocarcinoma (EAC) and its precursor, Barrett’s esophagus (BE), are associated with a pro-inflammatory, Gram-negative-dominated esophageal microbiome. We investigated whether Lactobacillus casei Shirota (LcS) consumption could shift the microbiome towards a more Gram-positive profile in BE patients. <h4>Design</h4> In a single-arm intervention study, 23 BE patients used LcS twice da...

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Literature Corpus work: 71290259-4551-5670-b6fa-9aa224a0b592
DOI: 10.1101/2025.05.12.25327438

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