Article
A T-Cell Epitope-Based Multi-Epitope Vaccine Designed Using Human HLA Specific T Cell Epitopes Induces Sterile Immunity against Experimental Visceral Leishmaniasis in Hamsters
2021-08-25
Abstract excerpt
Visceral Leishmaniasis is a neglected tropical disease affecting 12 million people annually. Even in the second decade of the 21st century, it has remained without an effective vaccine for human use. In the current study, we have designed three multiepitope vaccine candidates by the selection of multiple IFN-γ inducing MHC-I and MHC-II binder T-cell specific epitopes from 3 previously identified antigen gene...
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Identifiers and source
- Literature Corpus work
- 7001d41d-1928-5e1f-a0ec-5f25cfeaa968
- DOI
- 10.20944/preprints202108.0492.v1
