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A T-Cell Epitope-Based Multi-Epitope Vaccine Designed Using Human HLA Specific T Cell Epitopes Induces Sterile Immunity against Experimental Visceral Leishmaniasis in Hamsters

2021-08-25

Abstract excerpt

Visceral Leishmaniasis is a neglected tropical disease affecting 12 million people annually. Even in the second decade of the 21st century, it has remained without an effective vaccine for human use. In the current study, we have designed three multiepitope vaccine candidates by the selection of multiple IFN-γ inducing MHC-I and MHC-II binder T-cell specific epitopes from 3 previously identified antigen gene...

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Literature Corpus work
7001d41d-1928-5e1f-a0ec-5f25cfeaa968
DOI
10.20944/preprints202108.0492.v1
Open publication

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A T-Cell Epitope-Based Multi-Epitope Vaccine Designed Using Human HLA Specific T Cell Epitopes Induces Sterile Immunity against Experimental Visceral Leishmaniasis in HamstersDOI 10.20944/preprints202108.0492.v1
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