Article

Modelling erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I)

2019-08-30

Abstract excerpt

We employ and extensively characterise an ex vivo culture system to study terminal erythroid maturation of CD34 + progenitors from the peripheral blood of normal individuals and patients with Congenital Dyserythropoietic Anaemia type 1 (CDA-I). Using morphological analysis, FACS analysis and the proteomic approach CyTOF, we analysed patient-derived erythroblasts stage-matched with those from healthy donors durin...

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Literature Corpus work: 6f45c5e4-822b-5e03-904b-9917d851a478
DOI: 10.1101/744367

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