Article

Causal inference on microbiome-metabolome relations via <i>in silico in vivo</i> association pattern analyses

2021-03-16

Abstract excerpt

The effects of the microbiome on the host’s metabolism are core to understanding the role of the microbiome in health and disease. Herein, we develop the paradigm of in silico in vivo association pattern analyses, entailing a methodology to combine microbiome metabolome association studies with in silico constraint-based microbial community modelling. By dissecting confounding and causal paths, we show that in...

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Literature Corpus work: 6ecff7b9-b343-5d08-8e7b-ae7b37372281
DOI: 10.1101/2021.03.15.435397

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