Article

Monocytes as suitable carriers for dissemination of dengue viral infection

2022-10-01

Abstract excerpt

Dengue viruses (DENVs) exploit monocytes and macrophages for tropism and replication, therefore, establishing a long-term reservoir. However, their roles in dengue pathogenesis remains unclear. Here, using the human monocytic cell line THP-1, human primary monocytes, and non-human primate models, we show that DENV-infected monocytes represent suitable carriers for circulatory viral dissemination. Monocyte-derived...

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Literature Corpus work: 6e495af1-5776-5a0a-b728-e183a8e2c1ab
DOI: 10.1016/j.heliyon.2022.e11212

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