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Article

HIV-1 gp120 impairs spatial memory through CREB

2020-10-21

Abstract excerpt

<h4>SUMMARY</h4> HIV-associated neurocognitive disorders (HAND) remains an unsolved problem in the clinical management of HIV-1 carriers, because existing anti-retroviral therapy while suppressing viral replication, do not prevent neurocognitive impairment (e.g. spatial memory loss). HIV-1 gp120 protein has been proposed to contribute to HAND because it is shed by infected cells and the use of antibodies revealed...

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Literature Corpus work
6dc16ddd-ba16-508d-b791-8ebd4411fc48
DOI
10.1101/2020.10.20.347146
Open publication

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