Article

FGFR1 governs iron metabolism via regulating post-translational modification of IRP2 in prostate cancer cells

2022-10-26

Abstract excerpt

<h4>Background: </h4> The acquisition of ectopic fibroblast growth factor receptor 1 (FGFR1) expression is well documented in prostate cancer (PCa) progression. However, how FGFR1 facilitates PCa progression is not fully revealed, although it is known to confer tumor growth advantage and metastasis. Here we report that FGFR1 deletion in DU145 human PCa cells retards the iron metabolism and reduces transferrin rece...

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Literature Corpus work: 6d1efe00-95be-5fbb-b2d5-7cfc2a08c895
DOI: 10.21203/rs.3.rs-2178762/v1

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FGFR1 governs iron metabolism via regulating post-translational modification of IRP2 in prostate cancer cellsDOI 10.21203/rs.3.rs-2178762/v1Read

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