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Prognostic Impact of APOBEC3B Expression for Tumor-infiltrating Cytotoxic T cells in Metastatic Urothelial Carcinoma

2020-08-26

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<title>Abstract</title> <p><bold>Background: </bold>The APOBEC3B enzymes are endogenous carcinogenic mutagens. Metastatic urothelial carcinomas often harbor APOBEC3B-mediated mutations in which tCw to T or G substitution occurs. A high mutation burden in urothelial carcinoma can increase T-cell immunity against cancer cells, affecting prognosis. In this study, we aimed to evaluate patient survival and CD8+ T-cell...

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Literature Corpus work
6ba94c31-df3f-5080-906a-d8bcfe6a2b3b
DOI
10.21203/rs.3.rs-50129/v1
Open publication

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Prognostic Impact of APOBEC3B Expression for Tumor-infiltrating Cytotoxic T cells in Metastatic Urothelial CarcinomaDOI 10.21203/rs.3.rs-50129/v1
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