Article

Circular RNA detection identifies<i>circPSEN1</i>alterations in brain specific to Autosomal Dominant Alzheimer Disease

2021-10-30

Abstract excerpt

<h4>Background</h4> Autosomal-dominant Alzheimer’s disease (ADAD) is caused by pathogenic mutations in APP, PSEN1 , and PSEN2 , which usually lead to an early age at onset (<65). Circular RNAs are a family of non-coding RNAs highly expressed in the nervous system and especially in synapses. We aimed to investigate differences in brain gene expression of linear and circular transcripts from the three ADAD genes in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6b72a00d-5060-5db9-9d75-7c8173e498b8
DOI: 10.1101/2021.10.29.21265617

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Circular RNA detection identifies<i>circPSEN1</i>alterations in brain specific to Autosomal Dominant Alzheimer DiseaseDOI 10.1101/2021.10.29.21265617Read

Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease.Semantic proximity Read

Whole-Transcriptome Analysis of APP/PS1 Mouse Brain and Identification of circRNA-miRNA-mRNA Networks to Investigate AD PathogenesisSemantic proximity Read

Identification of circRNAs linked to Alzheimer’s disease and related dementiasSemantic proximity Read

Blood-Based Circular RNAs Enable Early and Accurate Alzheimer’s Disease DiagnosisSemantic proximity Read

Circular RNA (circRNA) in Alzheimer's disease (AD)Semantic proximity Read

Assessing circular RNAs in Alzheimer diseaseSemantic proximity Read

CircTulp4 functions in Alzheimer’s disease pathogenesis by regulating its parental gene, Tulp4Semantic proximity Read

I GF2R circular RNA hsa_circ_0131235 expression in the middle temporal cortex is associated with AD pathologySemantic proximity Read

Circular RNA expression and regulatory network prediction in posterior cingulate astrocytes in elderly subjectsSemantic proximity Read

Comprehensive analysis of differentially expressed profiles of Alzheimer’s disease associated circular RNAs in an Alzheimer’s disease mouse modelSemantic proximity Read

Differentially expressed circular RNAs in peripheral blood mononuclear cells of PD patientsSemantic proximity Read

Identification of circRNAs linked to Alzheimer's disease and related dementiasSemantic proximity Read