Frequency Chaos Game Representation - Singular Value Decomposition for Alignment-Free Phylogenetic Analysis

Abstract excerpt

This paper introduces ”SVD-FCGR,” a scalable and efficient frame-work for phylogenetic analysis using Singular Value Decomposition (SVD) on Frequency Chaos Game Representation (FCGR). Unlike traditional MSA techniques, SVD-FCGR handles large datasets with lower computational complexity. It supports both genome-wide and gene-specific analyses, as demonstrated with datasets of Japanese Encephalitis Virus (JEV), Hepa...

Topics

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• Algorithms
• Computational Biology
• Genome, Viral
• Genotype
• Mutation
• Neural Networks, Computer
• Papillomaviridae
• Phylogeny

Identifiers and source

Literature Corpus work

6abf7786-9935-5246-926a-b21072bac1ec

DOI

10.1101/2025.04.16.649090