Article

Muscle group specific transcriptomic and DNA methylation differences related to developmental patterning in FSHD

2021-09-30

Abstract excerpt

Muscle groups throughout the body are specialized in function and are specified during development by position specific gene regulatory networks. In developed tissue, myopathies affect muscle groups differently. Facioscapulohumeral muscular dystrophy, FSHD, affects upper body and tibialis anterior (TA) muscles earlier and more severely than others such as quadriceps. To investigate an epigenetic basis for suscepti...

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Literature Corpus work: 6a7ffd6a-d0e1-57fc-a8ee-108e6306d112
DOI: 10.1101/2021.09.28.462147

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