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Blood RNA signature RISK4LEP predicts leprosy years before clinical onset

1 Jun 2021

Abstract excerpt

BACKGROUND: Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is often late- or misdiagnosed leading to irreversible disabilities. Blood transcriptomic biomarkers that prospectively predict those who progress to leprosy (progressors) would allow early diagnosis, better treatment outcomes and facilitate interventions aimed at stopping bacterial transmission. To identify potential risk...

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PMID: 34090257
DOI: 10.1016/j.ebiom.2021.103379

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