Article

An integral genomic signature approach for tailored cancer targeted therapy using genome-wide sequencing data

2021-02-18

Abstract excerpt

<h4>ABSTRACT</h4> With the advent of low-cost sequencing, transcriptome and genome sequencing is expected to become clinical routine and transform precision oncology within next decade. However, viable genome-wide modeling methods that can facilitate rational selection of patients for tailored intervention while tolerating sequencing biases are far lacking. Here we propose an integral genomic signature (iGenSig)...

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Literature Corpus work: 6a17f5fd-2d09-5244-aa10-cfa7c1140403
DOI: 10.1101/2021.02.17.431663

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