In Silico Identification of Specialized Secretory-Organelle Proteins in Apicomplexan Parasites and In Vivo Validation in Toxoplasma gondii

Abstract excerpt

Apicomplexan parasites, including the human pathogens Toxoplasma gondii and Plasmodium falciparum, employ specialized secretory organelles (micronemes, rhoptries, dense granules) to invade and survive within host cells. Because molecules secreted from these organelles function at the host/parasite interface, their identification is important for understanding invasion mechanisms, and central to the development of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Heme Oxygenase-1 and Carbon Monoxide
• Share to Herpesvirus Infections and Treatments
• Share to Toxoplasma gondii Research Studies