Article

PhagePickr: A bacteria-centric computational tool for designing evolution-proof phage cocktails

2026-03-23

Abstract excerpt

As antibiotic resistance poses a major threat to global health, phage therapy offers an alternative to antibiotic treatments in the face of multidrug-resistant bacteria. However, host resistance to phages is also well-documented. Current computational tools for phage cocktail design do not explicitly address the evolution of phage resistance, let alone through the profiling of bacterial receptors whose variability...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 69ad4e55-067d-57f2-b60f-806558069315
DOI: 10.64898/2026.03.23.713575

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

PhagePickr: A bacteria-centric computational tool for designing evolution-proof phage cocktailsDOI 10.64898/2026.03.23.713575Read

Phylogeny-agnostic strain-level prediction of phage-host interactions from genomesSemantic proximity Read

Phylogeny-agnostic strain-level prediction of phage-host interactions from genomesSemantic proximity Read

NeoPhAR: Next-generation Phage Therapy for Antimicrobial ResistanceSemantic proximity Read

A Blueprint for Broadly Effective Bacteriophage Therapy Against Bacterial InfectionsSemantic proximity Read

Computational Basis for On-Demand Production of Diversified Therapeutic Phage CocktailsSemantic proximity Read

<strong>The Ecology of Phage Resistance: </strong><strong>The Key to Successful Phage Therapy?</strong>Semantic proximity Read

A comprehensive phage-bacteria interaction atlas links phage lineage and capsule serotype to genome-guided machine learning prediction in <i>Klebsiella pneumoniae</i>Semantic proximity Read

Systematic exploration of <i>Escherichia coli</i> phage-host interactions with the BASEL phage collectionSemantic proximity Read

Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection.Semantic proximity Read

Large scale phage-antibiotic combination studies reveal key combinations for urinary tract infection and urosepsis treatmentsSemantic proximity Read

Phage Therapy: Combating Evolution of Bacterial Resistance to PhagesSemantic proximity Read

Large scale phage-antibiotic combination studies reveal key combinations for urinary tract infection and urosepsis treatmentsSemantic proximity Read