Back to search

Article

Integrating single-cell and bulk RNA sequencing to identify TXNRD1 as effective target for prognostic and therapeutic strategy in Hepatocellular Carcinoma

2023-05-29

Abstract excerpt

Thioredoxin reductase (TXNRD1) acts as part of a major enforcer of redox homeostasis in the intracellular environment. However, its prognostic value and the relationship between TXNRD1 and core ferroptosis-related genes in hepatocellular carcinoma remain unclear. Here, we systematically analyzed and described the potential function and prognostic value of TXNRD1 in hepatocellular carcinoma. TXNRD1 was aberrantly e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
692fbdfd-b19a-50ff-b41f-2fbda92e2ddd
DOI
10.21203/rs.3.rs-2965547/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrating single-cell and bulk RNA sequencing to identify TXNRD1 as effective target for prognostic and therapeutic strategy in Hepatocellular CarcinomaDOI 10.21203/rs.3.rs-2965547/v1
Identification of ferroptosis-related genes for overall survival prediction in hepatocellular carcinomaSemantic proximity
Ferroptosis-Related lncRNAs Signature is a Prognostic Factor in Hepatocellular Carcinoma: A Study Based on TCGA DataSemantic proximity
A prognostic signature based on the expression profile of the ferroptosis-related long non-coding RNAs in hepatocellular carcinomaSemantic proximity
Identification of prognostic signatures of ferroptosis and autophagy-dependent lipid metabolism-related genes in hepatocellular carcinomaSemantic proximity
A novel single-cell model reveals ferroptosis-associated biomarkers for individualized therapy and prognostic prediction in hepatocellular carcinomaSemantic proximity
Development and validation of ferroptosis-related lncRNAs signature for hepatocellular carcinomaSemantic proximity
Identification of ferroptosis-related genes for overall survival prediction in hepatocellular carcinomaSemantic proximity
Construction of a Ferroptosis-Related Nine-lncRNA Signature for Predicting Prognosis and Immune Response in Hepatocellular CarcinomaSemantic proximity
Ferroptosis-related long non-coding RNA signature predicts the prognosis of hepatocellular carcinomaSemantic proximity
A Novel Ferroptosis-Related Long Non-Coding RNA Prognostic Signature Correlates With Genomic Heterogeneity, Immunosuppressive Phenotype, and Drug Sensitivity in Hepatocellular Carcinoma.Semantic proximity
Development and validation of four ferroptosis-related gene signatures and their correlations with immune implication in hepatocellular carcinomaSemantic proximity
A Mitophagy-Related Gene Signature for Subtype Identification and Prognosis Prediction of Hepatocellular CarcinomaSemantic proximity
Select a neighboring publication to make it the new centre.