Article

Methodological Analysis of Bias Risks in Adaptive Multi-Arm Platform Trials: A Case-Series from Three COVID-19 Studies

2026-01-06

Abstract excerpt

<p>Background: Adaptive platform trials (APTs) were widely promoted during the COVID-19 pandemic as an efficient and flexible approach for evaluating multiple interventions. However, their complexity and frequent protocol amendments may introduce risks of bias. We selected ivermectin as our case study both because of the marked discrepancy between the generally positive findings in the broader literature and the n...

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Literature Corpus work: 69130aac-aec0-55df-b089-a20fc018f816
DOI: 10.31222/osf.io/h5kc8_v1

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