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Impact of the MHRA Safety Update on Vitamin B 12 Testing and Coding in Metformin Users: A Retrospective Primary Care Analysis

2025-09-23

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<title>Abstract</title> <p> Background: Metformin is the most commonly prescribed first-line oral treatment for type 2 diabetes mellitus (T2DM) in the UK. Long-term therapy has been linked to vitamin B <sub>12</sub> deficiency, a concern recognised for decades but not consistently addressed. In June 2022, the UK Medicines and Healthcare products Regulatory Agency (MHRA) classified low vitamin B <sub>12</sub>...

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Literature Corpus work
68f9f742-4b17-50ba-8f8c-5e00ed19b992
DOI
10.21203/rs.3.rs-7306714/v1
Open publication

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Impact of the MHRA Safety Update on Vitamin B 12 Testing and Coding in Metformin Users: A Retrospective Primary Care AnalysisDOI 10.21203/rs.3.rs-7306714/v1
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