Article
Gene Network Inference from Single-Cell Omics Data and Domain Knowledge for Constructing COVID-19-Specific ICAM1-Associated Pathways
2022-02-11
Abstract excerpt
ICAM-1 is critical for interactions between cells. Previous studies have suggested that ICAM-1 triggers cell-to-cell transmission of HIV-1 or HTLV-1. SARS-CoV-2 shares several features with these viruses in interactions between cells, and SARS-CoV-2 cell-to-cell transmission is associated with COVID-19 severity. However, ICAM-1 and its associated pathways are not identified as essential factors in interactions bet...
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Identifiers and source
- Literature Corpus work
- 68419a24-d935-50a6-850d-c2c5aa5f5b32
- DOI
- 10.21203/rs.3.rs-1300133/v1
