Article

Physics-Informed Digital Twin Can Predict Cerebral Blood Flow and Cerebral Vascular Regulation Mechanisms in Neurocritical Care Patients

2025-05-23

Abstract excerpt

Cerebral blood flow is vital for brain function and is acutely controlled through a set of physiological mechanisms known as cerebral vascular regulation (CVR). It remains challenging to directly measure the dynamics and function of individual CVR mechanisms, limiting our ability to understand and optimize brain perfusion, particularly for neurologically injured patients. Digital twins offer an ideal tool for over...

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Literature Corpus work: 6830a0fd-537a-5788-b9e9-8669a14ed0f1
DOI: 10.1101/2025.05.22.655581

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