Article

Chondroprotective effects of bone marrow mesenchymal stem cell- derived exosomes in osteoarthritis

2023-10-05

Abstract excerpt

<h4>Objective: </h4> Chondrocyte ferroptosis constitutes a major cause of the development of osteoarthritis (OA). Bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) have a protective role against ferroptosis in various diseases. Hence, we aimed to determine whether BMSC-Exos alleviated chondrocyte ferroptosis and its effect on OA, and to dissect out the possible mechanisms. Methods An OA rat chondrocy...

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Literature Corpus work: 680ba102-950b-5303-8d95-658637840d51
DOI: 10.21203/rs.3.rs-3394654/v1

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