Article

One-to-one Benefit provided by Antioxidants to cultured skin Fibroblasts from Friedreich Ataxia patients

2024-04-28

Abstract excerpt

<h4>ABSTRACT</h4> With the hope of better understanding and characterizing the dramatic differences in antioxidant response of human cells carrying mutations in the frataxin gene responsible for Friedreich ataxia (FRDA), we studied primary cultures of skin fibroblasts derived from five FRDA patients harboring different large expansion sizes in the frataxin gene. Because oxidative stress was previously established...

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Literature Corpus work: 6701112e-5d51-536b-8d30-4dfa07343158
DOI: 10.1101/2024.04.25.591088

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