Article

Methodological Impacts on Microbiome Structure and Indicator Status in the Human Lower Respiratory Tract

2026-08-02

Abstract excerpt

<h4>Rationale</h4> Lung cancer is the leading cause of cancer-related death globally, and rising incidence among traditionally low-risk individuals intensifies the need for improved early-detection methods that the lower-airway microbiome may inform. <h4>Objectives</h4> To evaluate how respiratory tract sampling method shapes inferred microbiome structure, and whether bronchial brushing recovers a microbial comm...

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Literature Corpus work: 6634f4fd-e384-5e70-82b9-a42085abb73e
DOI: 10.64898/2026.08.02.742334

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