Article

Joint inference of discrete cell types and continuous type-specific variability in single-cell datasets with MMIDAS

2023-10-02

Abstract excerpt

Reproducible definition and identification of cell types is essential to enable investigations into their biological function, and understanding their relevance in the context of development, disease and evolution. Current approaches model variability in data as continuous latent factors, followed by clustering as a separate step, or immediately apply clustering on the data. We show that such approaches can suffer...

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Literature Corpus work: 65b26dfc-4597-5f6d-898c-7040be4b8bd8
DOI: 10.1101/2023.10.02.560574

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