Article

The impact of vaccine products, schedules and geographic regions on immunogenicity of pneumococcal vaccines in children under 2 years old: a systematic review and meta-analysis

2025-10-10

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Pneumococcal conjugate vaccines (PCVs) cover only a proportion of disease-causing serotypes. In some settings, population-level introduction of PCVs has resulted in an increase in “non-vaccine” serotype incidence. Higher-valency PCVs were developed to address shifting disease-causing serotypes. We aim to systematically define the trends in vaccine immunogenicity and likely pr...

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Literature Corpus work: 659997f0-03c1-55ac-8e05-2e0b3d3a7dbf
DOI: 10.1101/2025.10.10.25337708

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